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KMID : 1038620170350020185
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Radiation Oncology Journal
2017 Volume.35 No. 2 p.185 ~ p.188
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Extraordinary radiation super-sensitivity accompanying with sorafenib combination therapy: what lies beneath?
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Lee Ja-Young
Lee Ju-Hye
Yoon Han-Bin
Lee Ho-Jeong
Jeon Ho-Sang
Nam Ji-Ho
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Abstract
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Primary liver tumor, especially hepatocellular carcinoma (HCC), is a common cause of cancer death worldwide. The incidence is generally higher in Asian countries than in western countries. Carcinogenesis of HCC is often associated with hepatitis viral infections. Current standard treatment of HCC is surgical resection or transplantation in patients with early stage disease. However, the patient with advanced stage disease, surgical resection is often limited. Sorafenib or other treatment modalities are not so effective as well. We report a case of unusual radiation super-sensitivity in advanced stage HCC, and review the literature.
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KEYWORD
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Hepatocellular carcinoma, Radiotherapy, Sorafenib
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